姓名:付凤富
职称:教授
所在系:环境科学与工程系
研究方向:环境分析化学,食品安全分析,药物分析,毒理分析
个人简历:
付凤富,教授、博士生导师,福建省科技创新领军人才、福建省高层次B类人才、福建省百千万人才工程人选、福建省高校新世纪优秀人才。主要从事环境分析和环境污染与健康研究工作,在环境污染物的识别与检测和元素形态分析等方面具有丰富的基础理论知识和实际研究经验。主持国家重点研发计划课题、国家自然科学基金等国家级项目8项,卫生部公益项目子课题、福建省产学研重大项目和福建省科技厅重点项目等省部级项目10多项;发表SCI收录论文160余篇,被引5500多次,获授权国家发明专利10件,其中一件实现技术转让。获福建省科学技术进步奖二等奖和三等奖各1项(均排名第二)。承担本科生《分析化学》、博士生《现代分析技术》等课程的教学工作。
学术专著:
1, 陈国南,付凤富,谢剑炜,张忠平:“公共安全分析” in 《分析化学学科前沿与展望》(庄乾坤,刘虎威,陈洪渊主编),科学出版社,第一版,北京,2012。
社会兼职:
中国毒理学会分析毒理专业委员会委员
中华预防医学会食品卫生分会委员
《食品安全质量检测学报》编委
科研项目:
1,水环境中不同类型微/纳塑料对不同形态重金属离子的吸附特性及其复合毒性研究(国家基金),主持,70.2万,2023.1-2026.12。
2,海产品中砷和汞的形态特征及其生物利用率研究(福建省科技厅/引导性项目),主持,15万,2019.1-2022.12。
3,基于广谱特异性核酸适配体快速检测筛查环境和畜禽/鱼肉中磺胺类抗生素新方法研究(国家基金),主持,80万,2020.1-2023.12。
4,重要风险因子生物利用率研究(国家重点研究计划课题),主持,338万,已结题。
5,我国主要食用海藻中砷糖化合物的化学形态特征及其在动物体内的代谢变化研究(国家基金),主持,79万,已结题。
6,福建省科技创新领军人才项目,主持,80万,已结题。
7,基于纳米磁性粒子-抗体-金属标记技术和CE-ICP-MS分析检测海水和海产品中贝毒的新方法研究(国家基金),主持,80万,已结题。
8,不同起源气溶胶中主要金属离子的化学形态特征以及其对气溶胶的毒性和化学反应性影响的研究(国家基金),主持,20万,已结题。
9,关于不同起源的碳气溶胶的化学和物理特性的研究(国家基金),主持,35万,已结题。
10,大气中碳化物气溶胶的化学特性和表面形态的研究(国家基金),主持,25万,已结题。
11,纳米仿生生物探针检测环境和食品中重金属元素的研究(教育部博士点基金),主持,12万,已结题。
12,新型微流控芯片/毛细管电泳和ICPMS联用技术在元素形态和蛋白质分析上的应用研究(福建省新世纪优秀人才支持计划),主持,20万,已结题。
13,毛细管电泳/微流控芯片和电感耦合等离子体质谱仪联用技术的前期研究(福建省科技厅重点项目),主持,15万,已结题。
14,藻类食物中砷的形态分析方法的研究及福建省紫菜食物中无机砷限量建议值的制定(福建省科技厅重点项目),主持,15万,已结题。
15,食品安全应急与监测预警技术研究和应用(卫生部公益性行业重大专项子课题),主持,25万,已结题。
16,毛细管电泳和电感耦合等离子体质谱仪联用接口装置的产业化生产应用研究(科技厅产学研重大项目),主持,100万,已结题。
代表性论文(2018年以来发表的论文)
1, A Paper-Based Multicolor Colorimetric Aptasensor for the Visual Determination of Multiple Sulfonamides Based on Aptamer-Functionalized Magnetic Beads and NADH-Ascorbic Acid-Mediated Gold Nanobipyramids. Chemosensors, 2023, 11(7), 386.
2, Regulating the Growth Rate of Gold Nanobipyramids via a HCl-NADH-Ascorbic Acid System toward a Dual-Channel Multicolor Colorimetric Immunoassay for Simultaneously Screening and Detecting Multiple Sulfonamides. Analytical Chemistry, 2023, 95(27), 10438-10447.
3, Molecular probing of dissolved organic matter and its transformation in a woolen textile wastewater treatment station. Journal of Hazardous Materials, 2023, 457, 131807.
4, Colorimetric and visual determination of uric acid based on decolorization of manganese dioxide nanosheet dispersions. Microchimica Acta, 2023, 190(6), 217.
5, A multicolor immunosensor for the visual detection of six sulfonamides based on manganese dioxide nanosheet-mediated etching of gold nanobipyramids. Talanta, 2023, 258, 124449.
6, Broad-Specificity Aptamer of Sulfonamides: Isolation and Its Application in Simultaneous Detection of Multiple Sulfonamides in Fish Sample. Journal of Agricultural and Food Chemistry, 2022, 70(37), 11804-11812.
7, Sensitive detection and intracellular imaging of free copper ions based on DNA-templated silver nanoclusters aggregation-inducing fluorescence enhancement effect. Spectrochimica Acta Part A-Molecular and Biomolecular Spectroscopy, 2022, 283, 121734.
8, Near-Infrared Dye-Aptamer Assay for Small Molecule Detection in Complex Specimens. Analytical Chemistry, 2022, 94(28), 10082-10090.
9, Hybridizing Silver Nanoparticles in Hydrogel for High-Performance Flexible SERS Chips. ACS Applied Materials & Interfaces, 2022, 14(22), 26216-26224.
10, Hybridizing Carbon-Based Dot-Capped Manganese Dioxide Nanosheets and Gold Nanoparticles as a Highly Sensitive Surface-Enhanced Raman Scattering Substrate. Analytical Chemistry, 2021, 93(28), 9744-9751.
11, DNA-templated fluorescent silver nanoclusters on-off switch for specific and sensitive determination of organic mercury in seafood. Biosensors & Bioelectronics, 2021, 183, 113217.
12, In vitro bio-accessibility and distribution characteristic of each arsenic species in different fishes and shellfishes/shrimps collected from Fujian of China. Journal of Hazardous Materials, 2021, 420, 126660.
13, Improved grain yield and lowered arsenic accumulation in rice plants by inoculation with arsenite-oxidizing Achromobacter xylosoxidans GD03. Ecotoxicology and Environmental Safety, 2020, 206, 111229.
14, A universal method for the speciation analysis of arsenic in various seafood based on microwave-assisted extraction and ion chromatography-inductively coupled plasma mass spectrometry. Microchemical Journal, 2020, 159, 105592.
15, Carbon based dots capped tin oxide nanosheets hybridizing with silver nanoparticles for ultra-sensitive surface enhanced raman scattering substrate. Carbon, 2020, 170, 270-276.
16, A signal-on magnetic electrochemical immunosensor for ultra-sensitive detection of saxitoxin using palladium-doped graphitic carbon nitride-based non-competitive strategy. Biosensors & Bioelectronics, 128, 45-51.
17, Effect of selenium in soil on the 1 toxicity and uptake of arsenic in rice plant. Chemosphere, 2022, 14(22), 26216-26224.
18, Arsenic speciation on silver nanofilms by surface-enhanced Raman spectroscopy. Analytical Chemistry, 2019, 91, 8280-8288.
19, Persistent luminescent multifunctional drug delivery nano-platform based on persistent luminescent nanomaterial ZnGa2O4:Cr3+, Sn4+ for imaging-guided cancer chemotherapy. J. Mater. Chem. B, 2019, 7, 3019-3026.
20, Postsynthetic Functionalization of Zr4+ Immobilized Coreshell Structured Magnetic Covalent Organic Frameworks for Selective Enrichment of Phosphopeptides. ACS Applied Materials & Interfaces, 2019, 11, 13735-13741.
21, In Vitro Isolation of Class-Specific Oligonucleotide-Based Small-Molecule Receptors. Nucleic Acids Research, 2019, 47(12), e71.
22, A ratiometric nanoprobe for biosensing based on green fluorescent graphitic carbon nitride nanosheets as an internal reference and quenching platform. Biosensors and Bioelectronics, 129, 118-123, 2019.
23, A signal-on magnetic electrochemical immunosensor for sensitive detection of saxitoxin using palladium-doped graphitic carbon nitride-based non-competitive strategy. Biosensors and Bioelectronics, 128, 45-51, 2019.
24, Combination of Magnetic-Beads-Based Multiple Metal Nanoparticles Labeling with Hybridization Chain Reaction Amplification for Simultaneous Detection of Multiple Cancer Cells with Inductively Coupled Plasma Mass Spectrometry. Analytical Chemistry, 91, 1171-1177, 2019.
25, A colorimetric sensor for the visual detection of azodicarbonamide in flour based on azodicarbonamide-induced anti-aggregation of gold nanoparticles. ACS Sensors, 3, 2145-2151, 2018.
26, No structure-switching required: a generalizable exonuclease-mediated aptamer-based assay for small-molecule Ddetection. J. Am. Chem. Soc., 140, 9961-9971, 2018.
27, Facile synthesis of magnetic covalent organic framework nanobeads and application to magnetic solid-phase extraction of trace estrogens from human urine. Journal of Chromatography A, 1567, 136-146, 2018.
28, Boron- and phenyl-codoped graphitic carbon nitride with greatly enhanced light responsive range for photocatalytic disinfection. Journal of Hazardous Materials, 358, 62-68, 2018.
29, Species distribution characteristics of arsenic in shellfish seafood collected from Fujian Province of China. Journal of Food Composition and Analysis, 72, 132-140, 2018.
30, Tumor-targeting dual stimuli-responsive controllable release nanoplatform based on DNA-conjugated reduced graphene oxide for chemo-photothermal synergetic cancer therapy. J. Mater. Chem. B, 6, 4360-4367, 2018.
31, Colorimetric determination of glutathione by using a nanohybrid composed of manganese dioxide and carbon dots. Microchimica Acta, 185, 291(1-7), 2018.
32, Exonuclease-assisted multicolor aptasensor for visual detection of ochratoxin A based on G-quadruplex-hemin DNAzyme-mediated etching of gold nanorod. Microchimica Acta,185,259 (1-9),2018.
33, Introducing structure-switching functionality into small-molecule-binding aptamers via nuclease-directed truncation. Nucleic Acids Research, 46(13), e81, 2018.
34,Specifically and visually detect methyl-mercury and ethyl-mercury in fish sample based on DNA-templated alloy Ag-Au nanoparticles. Analytical Chemistry, 90, 5489-5495, 2018.
35,Effects of C-Related Dangling Bonds and Functional Groups on the Fluorescent and Electrochemiluminescent Properties of Carbon-Based Dots. Chem. Eur. J. 24, 1-6, 2018.
36, A palladium-doped graphitic carbon nitride nanosheet with high peroxidase-like activity: preparation, characterization and application in glucose detection. Particle and Particle Systems Characterization, 35(3), 1700359, 2018.
获奖情况:
1,藻类等海产品食物中砷的形态分析方法研究与应用,福建省2011年度科学技术进步三等奖(2011-J-3-035-2)。
2,食品安全分析与检测新技术开发及其示范应用,福建省2012年度科学技术进步二等奖 (2012-J-2-047-2)。